Radiotherapy for the palliation of painful bone metastases
نویسندگان
چکیده
منابع مشابه
Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases.
PURPOSE To compare pain relief among various dose-fractionation schedules of localized radiotherapy (RT) in the treatment of painful bone metastases. METHODS AND MATERIALS A systematic search for randomized trials of localized RT on bone metastases using different dose fractionations was performed using Medline (1966 to February 2001) and other sources. The primary outcomes of interest were c...
متن کاملRadiopharmaceuticals for the palliation of painful bone metastases.
Metastatic bone pain is prevalent in advanced cancer, and, despite a plethora of available therapies, effective palliation remains a clinical challenge. Bone-seeking radiopharmaceuticals are an often-overlooked but valuable analgesic option for select patients. These agents work by binding to hydroxyapatite at the tumor-bone interface of osteoblastic lesions, delivering therapeutic doses of rad...
متن کاملRe: Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases.
The role of radiotherapy in the palliation of painful symptomatic bone metastases is well established. Recently, it has been reported that single-fraction radiotherapy is as effective as multifraction radiotherapy ( 1 , 2 ) , which is the most widely used regimen. We read the interest the article by Hartsell et al. ( 3 ) , which compared the ability of a single 8-Gy fraction of radiation therap...
متن کاملRandomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases.
BACKGROUND Radiation therapy is effective in palliating pain from bone metastases. We investigated whether 8 Gy delivered in a single treatment fraction provides pain and narcotic relief that is equivalent to that of the standard treatment course of 30 Gy delivered in 10 treatment fractions over 2 weeks. METHODS A prospective, phase III randomized study of palliative radiation therapy was con...
متن کاملStereotactic body radiotherapy in the management of painful bone metastases.
More than 100,000 new cases of bone metastases are diagnosed each year, and they present an important clinical problem. They cause significant morbidity and quality-of-life issues in cancer patients. Conventional external-beam radiotherapy is currently the most common method to treat these metastases, with several randomized controlled trials showing no difference in effectiveness between multi...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2013
ISSN: 1465-1858
DOI: 10.1002/14651858.cd001793.pub2